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2017 Vol. 5, No. 2
Published: 2017-06-30

Case study
63 Traits of dietary behaviors and related nutrition problems in children with autism spectrum disorder
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.001
Autism spectrum disorder (ASD) is an neurodevelopmental disorder characterized by social (communication) impairments and restricted repetitive and stereotyped behavior and interests. Besides these core characteristics, children with ASD also have a tendency to suffer from unhealthy dietary behaviors, which may lead to a variety of secondary physical and mental problems. These unhealthy dietary behaviors have different manifestations and complicated reasons. This article mainly discusses the common traits of dietary behaviors, nutrition and related intestinal function in children with autism.
2017 Vol. 5 (2): 63- [Abstract] ( 2093 ) HTML (1 KB)  PDF (1457 KB)  ( 1706 )
67 Validity and reliability of inventory of callous-unemotional traits (parent version) in Chinese school-aged children
ZHANG Jinsong, ZHANG Huifeng, PAN Jingxue, SHUAI Lan, WANG Zhouye, XIA Weiping
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.002
Objective To evaluate the validity and reliability of inventory of callous-unemotional traits (ICU) parent version for school-aged children in China. Methods Parents of primary school students (n=200), non-reference clinical patients who were diagnosed as having attention-deficit hyperactivity disorders(ADHD) (n=206) by psychiatrist based on DSM-5 completed the ICU and Conners parent symptom questionnaire (PSQ). And 30 of them completed ICU retest after 2 weeks. Confirmatory factor analysis, concurrent validity, discriminative validity, internal consistency, and  test-retest reliability were used to evaluate the validity and reliability of ICU. Results Confirmatory factor analysis showed that the devised two-factor model of ICU was reasonable: χ2/df(116)=2.19, TLI=0.98, CFI=0.98, RMSEA=0.054. Subscales of ICU were correlated (r=0.19-0.42, P<0.05) with conduct problem, impulsive-hyperactivity and hyperactivity index of PSQ. ICU has good discriminate validity among ADHD and normal control groups (F=92.12-158.12, P<0.001). Cronbach α coefficient was 0.76-0.83 and retest reliability was 0.74-0.76. Conclusion The reliability and validity of ICU are satisfactory in Chinese school-aged children.
2017 Vol. 5 (2): 67- [Abstract] ( 2199 ) HTML (1 KB)  PDF (677 KB)  ( 1552 )
71 Development of college students' problematic mobile network usage behavior scale
JIANG Yongzhi, BAI Xiaoli, LIU Yong, ALATAN Bagen, LI Min, LIU Guiqin
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.003
Objective To evaluate the overuse behavior of mobile network, and to compile the questionnaire for the use of mobile network of college students. Methods Through literature review, open-ended interviews,  expert consultation, etc, we put forward the theory ideas of college students' problematic mobile network  use behavior scale, and carried out item analysis, exploratory factor analysis, confirmatory factor analysis, etc. Results The results showed that the scale included withdrawal symptoms, social soothes, impaired social function and increased tolerance, which accounted for 56.598% of the total variation. The verification factor analysis of the various fitting indexes basically met the requirements (χ2/df=5.567, GFI=0.982, AGFI=0.967, NFI=0.893, CFI=0.909, RMSEA=0.078). The scale had good reliability and validity index, and the internal consistency reliability coefficient was between 0.550 and 0.730, and the semi-reliability coefficient was between 0.532 and 0.745. Conclusion The scale can provide an effective tool for the measurement of college students' problematic  mobile network use behavior.
2017 Vol. 5 (2): 71- [Abstract] ( 2265 ) HTML (1 KB)  PDF (684 KB)  ( 1750 )
76 Analysis of fine motor ability in premature infants
ZHANG Guangbao, HE Yanlu, RUI Hongxin, WU Qian, DOU Shujuan, CHEN Yiqing, TONG Meiling, ZHANG Min, CHI Xia
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.004
Objective To explore the characteristics of fine motor ability in premature infants and provide the basis for the fine motor training. Methods The 86 premature infants from Obstetrics and Gynecology Hospital affiliated to Nanjing Medical University from April to November, 2016 were assessed by the Hong Kong preschool fine motor developmental assessment. Results There were no one good (0.0%); 36 premature infants were common (37.2%); 10 premature infants were poor (9.3%); and 40 premature infants were extremely poor (53.5%). Conclusion The fine motor ability of premature infants far lags behind  that of peers. It is helpful to early detection, early intervention and to improve the manipulative skills by using fine motor assessment.
2017 Vol. 5 (2): 76- [Abstract] ( 2078 ) HTML (1 KB)  PDF (656 KB)  ( 1861 )
79 Effects of authentic pride on interpersonal trust: multiple mediating roles of perspective taking and social support
HOU Lulu, JIANG Qi, WANG Huanzhen, LI Changran
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.005
Objective To explore the relationship of authentic pride on interpersonal trust and potential mediating effects of social support and perspective taking. Methods Pride scales, interpersonal trust scale, interpersonal reactivity index and social support rating scale were used to investigate 576 students from college first-year class to third-year class in Sichuan province and Chongqing, China. Results ① Significant positive correlations existed between authentic pride, perspective taking, social support, and interpersonal trust. ② Authentic pride positively affected interpersonal trust and the effects were produced primarily through the multiple mediating roles of social support and perspective taking. ③ Hubristic pride had no impact on interpersonal trust. Conclusion Authentic pride positively predicts interpersonal trust through the complete mediating effects of social support and perspective taking.
2017 Vol. 5 (2): 79- [Abstract] ( 1859 ) HTML (1 KB)  PDF (1072 KB)  ( 1483 )
85 Application of γ-amino-butyric acid inhibitory pathway in patients with neurodevelopmental disorders
JI Yiting, ZHANG Lingli, LI Fei
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.006
The maintenance of the physiological function of the central nervous system requires the coordination of the excitatory and inhibitory neural circuits. The γ-amino-butyric acid(GABA) is the primary inhibitory neurotransmitter in the adult brain. GABAergic responses undergo a switch from being excitatory to inhibitory in the early life. Increasing evidence has demonstrated the delay of switch results in the imbalance of excitatory and inhibitory neural circuits, and leads to the neurodevelopmental disorders, such as autism spectrum disorder(ASD), epilepsy, and schizophrenia. This review provides an overview of GABA and inhibitory neural circuits in neurodevelopmental disorders. It summerizes GABA inhibitory pathway in patients with neurodevelopmental disorders. In this way, it explores the possible direction of future research and the prospect of the application of this target.
2017 Vol. 5 (2): 85- [Abstract] ( 1956 ) HTML (1 KB)  PDF (704 KB)  ( 1257 )
89 Effects of early lifetime adversity and its enlightenment on early childhood education
LEI Mingxue, LI Chao
Phenotype of living creature is influenced by its hereditary and environment. As a kind of social creature, the development of human being is not only influenced by the natural environment, but also influenced by other individuals of human being. The experiences that undergoing adversity at the early age of lifetime, have effects not only on the progress of victim's development and the performance of behavioral and physiological condition, but also on the variety of corresponding epigenetic states. The variety of epigenetic states is not equal to the original DNA sequence changes, but may influence the offspring via intergenerational transmission. The influence may be transmitted by the “epigenetic-changed” germ cells or “epigenetic-changed” environment or behavior. As research indicated, “special-time” stimulation on the animals which suffered adversity at their early age, could reduce the bad performance which induced by the early-time adversity. It is worth to infant care and early education, especially to improve standard of early educational industry and to provide assistance to the exploited children.
2017 Vol. 5 (2): 89- [Abstract] ( 1736 ) HTML (1 KB)  PDF (689 KB)  ( 1283 )
95 Research progress of chronic stress on adolescent brain damage and implications for education
WANG Huiying,HAN Fei,ZHONG Nengzheng,LU Yaping
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.008
In recent years, the effects of stress on adolescence have attracted more and more attention. Because adolescent brains that  remain in development are very sensitive to stress, the accumulative effects of stress events during this period on the adult behavior are induced easily. These adult people are particularly sensitive to stress and  vulnerable to  anxiety, depression or other physical traumas. Studies show that the damage of exposure to stress to the brain is more serious in adolescence than that in adulthood. In the meantime, however, the plasticity of the brain during adolescence can be used as the right time of intervention to reduce later emotional and physical diseases. So, preventive measures or scientific interventions should be taken by school together with family and society to ensure adolescent brain development normally and to avoid causing the irreversible brain damage.
2017 Vol. 5 (2): 95- [Abstract] ( 2182 ) HTML (1 KB)  PDF (694 KB)  ( 1555 )
       Case study
101 Clinical manifestations and EEG patterns of Angelman syndrome
CAI Zhen, HE Dake, ZHANG Jianming, GE Xin, SONG Xiaoqing, WU Jing, YAN Yumei, HOU Ruolin
DOI: doi: 10.3969/j.issn.2095-4301.2017.02.009
Objective To investigate the clinical features and diagnosis of Angelman syndrome (AS). Methods The clinical manifestations, laboratory tests, and genetic tests of one case of AS were retrospectively analyzed. The related literature was reviewed. Results An 1-year-old female patient with motor and mental retardation had  seizures frequently. The EEG was abnormal. The chromosom karyotype was 46, XX, del (15) (q11.2q12), which had a deletion of chromosome 15. Conclusion In infants and young children with motor and mental retardation and epilepsy, genetic diseases should be considered. The test of chromosom and gene may help diagnosis.
2017 Vol. 5 (2): 101- [Abstract] ( 2057 ) HTML (1 KB)  PDF (2198 KB)  ( 1364 )
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