Abstract:China is in the era of second generation of one-child. How to shape children’s good behavior becomes the hot issue of parents’concern. Behavior is influenced by a variety of factors,such as temperament,cognitive limita?蛳tions,self-centered thinking,language development,parent behavior,family environment,and local culture. This paper adopts basic principles and technology of behavior change to illustrate the principle and application of conditioned reflex and operant conditioning reflection. It also introduces two basic principles and application examples for shaping children’s behavior in real life to provide guidance for pediatricians and parents.