Comparison of cardiopulmonary function between children with functional single ventricle and healthy children
YAN Xinxin, ZHOU Zhenfa, CHEN Weimin, WANG Tingting, HONG Haifa
Department of Thoracic and Cardiovascular Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Abstract:Objective To investigate the cardiopulmonary function of children with functional single ventricle after Fontan operation. Methods By noninvasive cardiopulmonary exercise testing (CPET), 39 children with functional single ventricle after Fontan operation were compared with healthy controls, and their cardiopulmonary function was analyzed. Results The general demographic data of children with functional single ventricle were similar to those of the healthy control group. For the core index of CPET, oxygen uptake at anaerobic threshold of the children with functional single ventricle was significantly lower than that of the control group[ (15.6±4.6)mL/(min·kg) vs. (29.1±6.4)mL/(min·kg)]with percentage of estimated maximum oxygen uptake [(39.3±11.1)% vs. (71.0±14.0)%]. The oxygen uptake under extreme conditions of the children with functional single ventricle was significantly lower than that of the control group [(23.7±5.3)mL/(min·kg) vs. (43.5±7.5)mL/(min·kg)]with percentage of estimated maximum oxygen uptake [(59.9±13.6)% vs. (107.0±17.0)%] (P<0.000 1). Conclusion The cardiopulmonary function of children with functional single ventricle is significantly lower than that of the healthy controls, so exercise intervention is recommended.
严欣欣,周振发,陈伟敏,王婷婷,洪海筏. 功能性单心室患儿与健康儿童的心肺功能比较[J]. 教育生物学杂志, 2021, 9(6): 473-.
YAN Xinxin, ZHOU Zhenfa, CHEN Weimin, WANG Tingting, HONG Haifa. Comparison of cardiopulmonary function between children with functional single ventricle and healthy children. JOURNAL OF BIO-EDUCATION, 2021, 9(6): 473-.