Advances in repetitive transcranial magnetic stimulation for children and adolescents with depression
LAI Qingjuan, CAO Qingjiu
Institute of Mental Health，National Health Commission Key Laboratory of Mental Health, Peking University; National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, Beijing 100083, China
摘要儿童青少年抑郁症的发病率逐年升高，给患者、家属带来痛苦，造成社会功能损害。心理治疗及抗抑郁药治疗是治疗儿童青少年抑郁的重要手段，但心理治疗获得性较差，而抗抑郁药治疗会增加自杀风险，需要开发其他有效的治疗方法，包括物理治疗方法。重复经颅磁刺激(repetitive transcranial magnetic stimulation, rTMS)技术已被美国食品药品管理局(Food and Drug Administration, FDA)批准用于成人抑郁症的治疗，该方法具有无创、安全性较高的优点，对部分难治性患者亦有效，但在儿童青少年中积累的经验尚不多。综述国内外rTMS治疗儿童青少年抑郁症的研究进展，以期为在儿童青少年抑郁症中开展此项治疗寻找证据。
Abstract：The lifetime prevalence of depression in children and adolescents has increased year by year. Depression not only causes suffering in patients, but also increases the burden on families and society. Contemporary treatment approaches for children and adolescents with depression are psychotherapy and antidepressant treatment. However, the effectiveness of these methods is usually unsatisfied. Even worse, there is the possibility that antidepressants could increase the suicide risk. Therefore, it is necessary to develop other effective treatment approaches, including physical therapy methods. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive treatment that has achieved promised effects on the treatment of adult depression. And it has been approved by the American Food and Drug Administration (FDA) to treat adults (22 years of age or older) who have failed to improve with prior antidepressant treatment. But the use of rTMS in the treatment for children with depression is limited，and there is not enough experience accumulated in this field. This article reviews the recent studies on the use of rTMS in the treatment of depression in children and adolescents, with an objective for seeking evidence for this treatment in children and adolescents with depression.
来庆娟，曹庆久. 重复经颅磁刺激治疗儿童青少年抑郁症研究进展[J]. 教育生物学杂志, 2021, 9(2): 79-.
LAI Qingjuan, CAO Qingjiu. Advances in repetitive transcranial magnetic stimulation for children and adolescents with depression. JOURNAL OF BIO-EDUCATION, 2021, 9(2): 79-.
