Objective　To discuss effectiveness of physical education in empathy intervention for students majoring in physical education. Methods　A total of 392 college students were selected as research objects, and questionnaire survey was adopted to assess empathy ability. SPSS 21.0 was used for data analysis. Results　Boys had higher cognitive and emotional empathy than girls. The empathy ability of physical education students was higher than that of non-physical education students. There was a negative correlation between grades of physical education majors and emotional empathy. Conclusion　There are differences in empathy ability between sports majors and non-sports majors. Physical education is effective in empathy intervention for physical education students.