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| Advances in imaging studies on neural mechanism of Tourette's syndrome |
| ZHOU Yifang1,2, SUN Kexing2, WANG Xuefeng3 |
| 1．Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China；2．Department of Traditional Chinese Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China；3．Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China |
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Abstract Tourette syndrome(TS)is a kind of neurodevelopmental disorder in children and adolescents. Its pathophysiology is still unclear. In recent years, imaging research has gradually pointed to the corticostriatothalamocortical(CSTC)circuit. The applications of positron emission tomography(PET), functional magnetic resonance imaging(fMRI), and functional nearinfrared spectroscopy(fNIRS)provide an objective basis for elucidating the neurophysiological mechanism of TS. This article reviews the changes of CSTC circuit in TS patients from the perspective of structure and functional neuroimaging.
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