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| Effect of early intervention on mental and motor development in late preterm infants |
| WANG Tingxue1，LI Bei2，XU Bing1，HU Wen1，JIANG Qi’an1，XU Xiu2 |
1. Department of Child Heathcare，Shanghai Pudong New Area Maternal and Child Healthcare Hospital，Shanghai 201206，China；2. Department of Child Heathcare，Children’s Hospital affiliated to Fudan University，Shanghai 201102，China |
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Abstract Objective To investigate the effect of early intervention on mental and motor development in late preterm infants（LPIs）. Methods Two hundred and seven LPIs were divided into LPIs intervention group（122 cases）and LPIs control group（85 cases）based on the time of follow-up and voluntariness of parents，and another 54 full-term infants（FTIs）were served as FTIs group. Follow-up was carried out in three groups，and early intervention was conducted in LPIs intervention group. Assessments were performed in three groups at corrected ages of（3 ± 0.7），（6 ± 0.7）and（12 ± 0.7）months using the Bayley Scales of Infant Development，Second Edition，and mental development index（MDI）and psychomotor development index（PDI）were calculated. Questionnaire survey on compliance was done among mothers in LPIs intervention group，and the results were analyzed. Results A complete follow-up was done in 83 cases in LPIs intervention group，42 cases in LPIs control group and 43 cases in FTIs group. The PDI and MDI values gradually increased with ages in LPIs intervention group. There was no significant difference in PDI and MDI values between LPIs intervention group and LPIs control group at the age of 3 months（P > 0.05），while the PDI and MDI values in LPIs intervention group were significantly higher than those in LPIs control group at the age of 6 and 12 months（P < 0.05）. The PDI and MDI values in LPIs intervention group and LPIs control group were significantly lower than those in FTIs group at the age of 3，6 and 12 months（P < 0.05）. Questionnaire survey on compliance in LPIs intervention group indicated that the role of doctors in relieving the anxiety of parents helped the parents to complete the routine follow-up. Conclusion The cognitive and motor development of LPIs lags behind FTIs. Early intervention may improve the cognitive and motor development of LPIs. The early intervention program for LPIs remains to be perfected.
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