Association of risk of autism spectrum disorder with early life exposure to particulate matter: research progress and prospects
GU Wenmin1, JI Xing2
1. Shanghai No.25 Middle School, Shanghai 200090, China; 2. Department of Developmental and Behavioral Pediatric and Child Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Abstract：Autism spectrum disorder（ASD）is a severe neurodevelopmental disorder in children. Currently, the pathology and causes of ASD remain unclear. Although genetic factors play an important role in ASD, only a small proportion of ASD cases can be explained by chromosomal abnormalities or monogenic variations. It is generally believed that the genetic and environmental interaction is essential in the pathogenesis of ASD. Air pollution is one of the major problemsfaced by human society, and particulate matter 2.5（PM2.5）is an important air pollutant. In recent years, many studies have focused on the association of the risk of ASD with early life exposure to PM2.5. This article reviews this issue, and discusses the limitations of current research and future research directions.
顾雯敏，季 星. 生命早期细颗粒物暴露与孤独症谱系障碍患病风险相关性的研究进展和展望[J]. 教育生物学杂志, 2025, 13(1): 64-.
GU Wenmin, JI Xing. Association of risk of autism spectrum disorder with early life exposure to particulate matter: research progress and prospects. JOURNAL OF BIO-EDUCATION, 2025, 13(1): 64-.
