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| Correlation analysis between bone strength and scoliosis angle in female adolescent idiopathic scoliosis |
| LI Huizhen1, ZHOU Xuan1, CHEN Nan1, LI Xin1, LIANG Juping1, WU Dongyu2, JIN Mengdie1, SONG Yuanyuan2, DU Qing1 |
| 1．Department of Rehabilitation Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China；2．Department of Rehabilitation Medicine, Chongming Branch of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 202150, China |
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Abstract Objective To investigate the correlation between bone strength and the scoliosis angle in female adolescent idiopathic scoliosis (AIS). Methods Newly diagnosed AIS female patients aged 10－17 in the Rehabilitation Department, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine were selected from March 2018 to October 2019. General information such as age, height, weight, and age at menarche were collected. The severity of scoliosis (Cobb angle) and bone maturity (Risser sign) were evaluated by full spine X-ray; and bone strength [(speed of sound (SOS)] was detected by ultrasound bone strength meter. And linear regression was used to analyze the correlation between SOS value and Cobb angle. Results A total of 403 female patients, aged (13.19±1.75) years old, with a Cobb angle of 10°－59° were included in this study. The crude analysis showed there was no correlation between the SOS value and the Cobb angle(r＝－0.092，P＝0.065). After adjustment for age, height, weight and Risser sign, the SOS value was negatively correlated with the Cobb angle in female AIS patients (β＝－1.705，P＝0.010). Conclusion The Cobb angle of female AIS is correlated with bone strength, and the bone strength is lower in patients with large Cobb angle.
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