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| Effect of iron nutritional status during pregnancy on iron deficiency anemia in infants aged 6-12 months |
| CHEN Chengdi, LIN Yuanyuan, ZHANG Yiwen |
| Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China |
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Abstract Objective To explore the iron nutritional status during pregnancy and its influence on iron deficiency anemia (IDA) of infants by screening and analyzing the influencing factors of IDA of infants aged 6-12 months, so as to provide scientific basis for the prevention and treatment of infant anemia. Methods The infants aged 6-12 months who underwent physical examination in Shanghai Wellem Clinic from January 2019 to June 2020 were enrolled. And the data of routine health examination (physical examination, blood routine test, iron metabolism examination, and questionnaire survey) were analyzed retrospectively. Results Among 342 infants aged 6-12 months, 51 infants with IDA were detected, accounting for 14.91%. Maternal anemia during pregnancy was 26.90%, including 19.57% in early pregnancy, 55.43% in middle pregnancy, and 23.91% in late pregnancy. Maternal iron supplementation during pregnancy accounted for 34.80%. The results of grouping analysis showed that between IDA group and non-IDA group, there were significant differences in maternal iron nutrition status (anemia during pregnancy, iron supplement during pregnancy, and recovery of anemia during pregnancy), maternal body mass index (BMI), and infant birth weight (P<0.05). After adjusting maternal BMI and infant birth weight, Logistic regression analysis showed that maternal anemia during pregnancy was still a risk factor for infant with IDA (OR>1, P<0.05). Conclusion Anemia during pregnancy is the main risk factor of IDA in infants aged 6-12 months. Prevention of anemia during pregnancy is key to prevent IDA in infants.
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