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| Correlation between nocturnal enuresis and repeated upper respiratory tract infection in children |
| ZHENG Xiangyu1, LI Shenghui2, MA Jun1 |
| 1. Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Children's Medical Center, Shanghai 200127, China；2. Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China |
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Abstract Objective To investigate the relationship between nocturnal enuresis and repeated upper respiratory tract infection in children, and provide empirical evidence for further understanding of enuresis in children. Methods The samples were collected from the national sleep survey of school-age children from November to December in 2005. A total of 23 791 children from nine cities were investigated, and 21 980 children were enrolled in this study. The general condition and sleep condition of children were investigated by using questionnaires, which included personal status and family environment of school-age children and sleep habits of children. A multivariate Logistic regression model was constructed to investigate the relationship between nocturnal enuresis and recurrent upper respiratory tract infection in children. Results The incidence of recurrent upper respiratory tract infection in children was 17.1%. The univariate analysis results of repeated upper respiratory tract infection and related factors were enuresis, age, family per capita monthly income <800 yuan or 800～1 500 yuan, food and drug allergy, and learning difficulties. These factors might be risk factors for recurrent upper respiratory tract infection. After controlling for confounding variables, the results of multivariate analysis showed that nocturnal enuresis might be risk factors for recurrent upper respiratory tract infection (OR＝1.365, 95% CI 1.170－1.592, P<0.01). The effect of nocturnal enuresis (OR＝1.551, 95% CI 1.223－1.966, P<0.01) on the occurrence of recurrent upper respiratory tract infection was greater in girls than that in boys (OR＝1.228, 95% CI 1.001－1.505, P<0.05). Conclusion The incidence of enuresis in children increased the risk of recurrent upper respiratory tract infections, and this increase was more pronounced in girls. It is suggested that timely treatment of enuresis in children has certain clinical significance in preventing and treating repeated upper respiratory tract infection.
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