Recent advances in etiological study of primary nocturnal enuresis
ZHANG Anyi, MA Jun
Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Abstract：Primary nocturnal enuresis(PNE) is a kind of disease that when a child's age and mental age is over five, he or she still could not wake up to void in the night, and urinate on the bed at last. It is associated with many physical and mental diseases, and damages the child's physical and mental health seriously. In recent years, the prevalence of PNE is climbing high, and the studies about the etiology of PNE are becoming more and more. Recently, the major etiological viewpoints are: heredity, reversed anti-diuretic hormone circadian rhythm, bladder dysfunction, co-sleeping, deep sleep, abnormal central nervous system, psychological factors, and so on. Meanwhile, PNE is also related to the environmental factors, so PNE is caused by a lot of factors, which acted in common.
